Circadian Rhythms: An Electric Jolt to the Clock
نویسنده
چکیده
The animal circadian pacemaker is composed of two transcriptional feedback loops, which regulate electrical activity in circadian neurons. Surprisingly, a new study reports that electrical activity can reprogram circadian transcription, and identifies CREB proteins as candidates for this reprograming.
منابع مشابه
Influence of N-Phthaloyl GABA on the Circadian Rhythms of Lipid Peroxidation and Antioxidants in Wistar Rats under Constant Light
N-Phthaloyl GABA was administrated daily (50 mg/Kg body weight-i.p) to Wistar rats for 21 days and circadian rhythms of thiobarbituric acid reactive substances (TBARS) and antioxidants such as reduced glutathione (GSH), catalase (CAT) and superoxide dismutase (SOD) were studied under constant light (LL) conditions. Delayed acrophase of TBARS and advanced acrophase of antioxidants (GSH, CAT and ...
متن کاملEffects of Lycium barbarum. polysaccharide on type 2 diabetes mellitus rats by regulating biological rhythms
Objective(s): Type 2 diabetes mellitus (T2DM) is associated with circadian disruption. Our previous experimental results have showed that dietary Lycium barbarum. polysaccharide (LBP-4a) exhibited hypoglycemic and improving insulin resistance (IR) activities. This study was to explore the mechanisms of LBP-4a for improving hyperglycemia and IR by regulating biological rhythms in T2DM rats. Mat...
متن کاملEffect of an Antagonist of Vasoactive Intestinal Polypeptide on Biological Rhythm of Rest Activity in the Rat
Abstract Vasoactive Intestinal Polypeptide (VIP), has been found in different neurotransmitter systems and exists in various nerve tracts in the brain. Potential role of this peptide in physiological processes such as regulation of sleep and wakefulness, and biological rhythms has been confirmed in several reports. In the present research effects of intracerebroventricular (ICV) injection of a...
متن کاملEffect of Circadian Rhythm on Antiulcer Activity of Hydroxyzine in Cold Stress Induced Ulcer in Wistar Albino Rats
Circadian rhythms are driven by endogenous clock gene and affects in several gastric parameters causing ulcerogenesis. The study was aimed to evaluate the time dependent antiulcer activity of hydroxyzine in cold-stress-induced ulcer model. The ulcer protection effect of hydroxyzine was studied at various time intervals (9 am, 1 pm, 5 pm, 91 pm, 1 am and 5 am) in cold stress ulcer model using wi...
متن کاملCircadian Control of Eclosion Interaction between a Central and Peripheral Clock in Drosophila melanogaster
Drosophila melanogaster display overt circadian rhythms in rest:activity behavior and eclosion. These rhythms have an endogenous period of approximately 24 hr and can adjust or "entrain" to environmental inputs such as light. Circadian rhythms depend upon a functioning molecular clock that includes the core clock genes period and timeless (reviewed in and ). Although we know that a clock in the...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Current Biology
دوره 22 شماره
صفحات -
تاریخ انتشار 2012